
Can Epidural Steroid Injections Affect Menstrual Cycle?
Epidural steroid injections may, in rare cases, affect a person’s menstrual cycle, although this is not a common side effect. The hormones in the steroid medication can cause changes in the menstrual cycle, such as delayed periods or heavier bleeding. The hormones in the steroid medication can cause temporary changes in menstruation, such as delayed periods or heavier bleeding, though these effects are typically short-term and resolve once the medication is metabolised.
Understanding Epidural Steroid Injections
Epidural steroid injections are a targeted treatment for managing inflammation and pain associated with various spinal conditions. By delivering a corticosteroid and sometimes an anaesthetic directly into the epidural space of the spine, these injections help reduce swelling around the affected nerves, relieving pain and enhancing mobility
The Role of Steroids in Pain Relief
Steroid medications, such as corticosteroids, are powerful anti-inflammatory agents that help to reduce swelling and irritation around the nerves. They are used to relieve pain, improve mobility, and address issues related to spinal conditions.
How the Procedure Works
The procedure is typically performed under ultrasound guidance to ensure precise placement of the needle. This reduces the risk of complications and increases the efficacy of the treatment.

Hormonal Effects of Epidural Steroid Injections
Corticosteroids, which are used in epidural steroid injections, are synthetic versions of hormones produced by the adrenal glands. They can have a significant impact on various bodily systems, including the reproductive system.
Steroid and Hormonal Disruption
Corticosteroids can interfere with the hormonal balance of the body, including the regulation of cortisol and other hormones involved in menstruation. This can lead to temporary disruptions in the menstrual cycle.The Impact on the Menstrual Cycle
Some people may experience changes in their menstrual cycle after receiving an epidural steroid injection. These changes can include delayed periods, heavier bleeding, or missed cycles. However, these effects are typically short-term and should resolve once the steroid medication is metabolised.
Possible Causes of Menstrual Changes Following an Epidural Injection
Corticosteroids and Hormonal Fluctuations
Corticosteroids work by mimicking the body’s natural stress hormones, such as cortisol. These hormonal fluctuations can impact the hypothalamic-pituitary-gonadal (HPG) axis, which controls the menstrual cycle. As a result, individuals may notice alterations in the timing or flow of their periods.
Stress Response and Menstruation
The administration of steroids can simulate a stress response in the body, which may affect reproductive hormones and cause temporary disruptions to the regularity of menstruation.
Risk Factors for Menstrual Changes
Not everyone will experience menstrual irregularities following an epidural steroid injection. However, certain factors may increase the likelihood of these changes.
Pre-existing Hormonal Imbalances
Women with pre-existing conditions such as polycystic ovary syndrome (PCOS), thyroid imbalances, or endometriosis may be more susceptible to changes in their menstrual cycle when exposed to corticosteroids.Frequency and Dosage of Steroid Injections
Those who receive frequent or higher-dose epidural steroid injections are more likely to experience disruptions in their hormonal regulation. Multiple injections over time can have a cumulative effect on the body’s hormonal balance.
Duration of Menstrual Cycle Changes
In most cases, any changes to the menstrual cycle caused by epidural steroid injections are temporary.
Reversal of Effects
Once the steroid is metabolised and removed from the body, menstrual cycles generally return to normal. Any disruptions, such as delayed periods or increased bleeding, tend to resolve within a few weeks.When to Seek Medical Advice
If menstrual changes persist for longer than expected or if they are accompanied by other unusual symptoms, it is important to consult with a clinician to ensure that there are no underlying issues.
The Benefits of Ultrasound-Guided Epidural Steroid Injections
At Joint Injections, we specialise in ultrasound-guided procedures, which offer several advantages over traditional methods.
Improved Accuracy and Safety
Using ultrasound guidance allows for more precise placement of the needle, ensuring the steroid medication is delivered to the exact area of inflammation. This enhances the effectiveness of the injection and reduces the risk of complications.Minimising Risk of Side Effects
The use of ultrasound helps minimise the risk of inadvertently injecting the steroid into surrounding tissues, such as blood vessels or organs. This makes the procedure safer, especially for individuals who may be concerned about potential side effects, including those affecting the menstrual cycle.
When Epidural Steroid Injections Are Recommended
Epidural steroid injections are typically recommended when more conservative treatments, such as physical therapy or oral medications, have not provided adequate relief from symptoms.
Conditions Treated with Epidural Steroid Injections
Epidural steroid injections are effective for conditions such as sciatica, herniated discs, spinal stenosis, and degenerative disc disease. By reducing inflammation, these injections can help alleviate pain and improve mobility.Assessing Candidacy for the Procedure
A thorough evaluation by a clinician is essential before proceeding with an epidural steroid injection. Factors such as medical history, current symptoms, and response to other treatments will determine whether this injection is the right choice for a given patient.

Conditions Treated with Epidural Steroid Injections
Epidural steroid injections are most commonly used to treat conditions such as:
- Herniated Discs: These injections can help reduce inflammation around the affected disc and nerve root, offering significant pain relief.
- Spinal Stenosis: When the spinal canal narrows, it can compress nerves. Epidural steroid injections help reduce this pressure.
- Sciatica: Radiculopathy caused by compression of the sciatic nerve can benefit from targeted injections that reduce nerve irritation.
- Degenerative Disc Disease: Chronic back pain caused by the degeneration of intervertebral discs can also be managed with epidural steroid injections.
The Procedure for Epidural Steroid Injections
The procedure for receiving an epidural steroid injection involves several key steps, which are designed to ensure patient safety and optimal results.
- Preparation for the Injection
Before the procedure, the patient is typically positioned on an examination table. The area around the injection site is cleaned, and a local anaesthetic is used to numb the skin and deeper tissues. - Steroid Injection Administration
The injection is performed under ultrasound guidance to ensure the needle is placed accurately in the epidural space. Once the needle is in place, the steroid medication is slowly injected. - Post-Injection Care
After the injection, the patient is monitored for a short period to ensure no immediate complications occur. Most people can resume their normal activities within a day or two, although strenuous exercise should be avoided for a few days.
Let's start your journey with us:
- Find your nearest clinic from our Multiple Locations.
- Call us on 020 8870 8761 or email us at: info@joint-injections.co.uk to book your appointment.
- Comprehensive Musculoskeletal examination and testing.
- Same day Ultrasound Guided Injection for pain relief.
- Fixed fee structure so you can plan your expenses.
Post-Injection Monitoring and Aftercare
Post-injection care plays an important role in ensuring the success of the treatment and preventing complications.
- Monitoring for Immediate Side Effects
After the injection, patients are usually observed for a short time to ensure that there are no immediate adverse reactions, such as severe dizziness or difficulty breathing. These reactions are rare, but it is important to be monitored during the recovery phase. - Managing Pain and Discomfort
Some mild discomfort, such as soreness at the injection site or a slight headache, is common after the procedure. Over-the-counter pain medications can help alleviate these symptoms.
Recovery After Epidural Steroid Injections
Following an epidural steroid injection, patients should:
- Rest for the first 24 hours.
- Gradually resume normal activities as directed by their clinician.
- Avoid strenuous activities or lifting heavy weights for a few days.
- Follow up with the clinician to assess the effectiveness of the injection and discuss any potential adjustments to treatment.
Effectiveness of Epidural Steroid Injections
The effectiveness of epidural steroid injections varies from patient to patient. Some individuals experience immediate relief, while others may take a few days to feel the effects. In most cases, the injections can significantly reduce pain and inflammation, with the benefits lasting from weeks to months.
Impact of Epidural Steroid Injections on Menstrual Cycles
Epidural steroid injections are a valuable treatment option for various spinal conditions, offering significant pain relief. While these injections can affect the menstrual cycle in some individuals, such effects are typically short-lived and resolve once the steroid medication is cleared from the body. If you experience persistent menstrual irregularities after an epidural injection, it is important to consult with your clinician to explore further options.
Explore Other Treatment Options

Hyaluronic Acid Injections
Hyaluronic acid (HA) injections can help improve joint lubrication by replenishing the natural hyaluronic acid found within the joint. This may reduce friction between joint surfaces, support smoother movement and help improve comfort during everyday activities.

PRP Injections
Platelet-rich plasma (PRP) injections use a concentrated preparation of your own platelets to support the body’s natural healing processes within the affected joint. They may help support tissue repair, reduce discomfort and promote improved joint function and mobility.
FAQs: Can Epidural Steroid Injections Affect Your Menstrual Cycle?
Can an epidural steroid injection affect my menstrual cycle?
Corticosteroids can occasionally cause temporary changes to the menstrual cycle, such as irregular timing, lighter or heavier bleeding, or spotting. This is not common, but it has been reported following steroid injections. If you notice any changes, it’s worth mentioning them at your next follow-up.
Why would a steroid injection affect periods if it's given in the spine, not the bloodstream?
Although an epidural steroid injection is delivered locally, a small amount of the corticosteroid can be absorbed into the bloodstream. This systemic absorption is what can occasionally lead to hormonal or cycle-related effects, in the same way oral or intramuscular steroids can.
How long do any changes to my cycle usually last?
Where changes do occur, they tend to be temporary and typically resolve within one to two cycles as the steroid clears from the body.
Should I avoid scheduling my injection around my period?
There’s no strict clinical requirement to time your injection around your cycle. If you have a preference or concerns, you can discuss timing with our clinician at your consultation.
Could something else be causing the change, rather than the injection?
Possibly — menstrual cycle changes can have many causes, including stress, illness, or unrelated hormonal factors. If changes persist beyond a couple of cycles or you’re unsure, it’s worth having this checked rather than assuming it’s related to the injection.


